APPBP2 Back

amyloid beta precursor protein (cytoplasmic tail) binding protein 2

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NCBI Description of APPBP2

The protein encoded by this gene interacts with microtubules and is functionally associated with beta-amyloid precursor protein transport and/or processing. The beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. This gene has been found to be highly expressed in breast cancer. Multiple polyadenylation sites have been found for this gene.

Community Annotation of APPBP2 Add / Edit APPBP2: Annotations

No community annotations yet for APPBP2.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

APPBP2 is highly significantly mutated in
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APPBP2 is significantly mutated in
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APPBP2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for APPBP2