APOL4 Back

apolipoprotein L, 4

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NCBI Description of APOL4

The protein encoded by this gene is a member of the apolipoprotein L family and may play a role in lipid exchange and transport throughout the body, as well as in reverse cholesterol transport from peripheral cells to the liver. Two transcript variants encoding two different isoforms have been found for this gene. Only one of the isoforms appears to be a secreted protein.

Community Annotation of APOL4 Add / Edit APOL4: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


APOL4 is highly significantly mutated in
APOL4 is significantly mutated in
APOL4 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for APOL4