APOC4 Back

apolipoprotein C-IV

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NCBI Description of APOC4
This gene encodes a lipid-binding protein belonging to the apolipoprotein gene family. The protein is thought to play a role in lipid metabolism. Polymorphisms in this gene may influence circulating lipid levels and may be associated with coronary artery disease risk. This gene is present in a cluster with other related apolipoprotein genes on chromosome 19. Naturally occurring read-through transcription exists between this gene and the neighboring downstream apolipoprotein C-II (APOC2) gene.

Community Annotation of APOC4 Add / Edit APOC4: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

APOC4 is highly significantly mutated in
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APOC4 is significantly mutated in
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APOC4 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for APOC4