APOC1 Back

apolipoprotein C-I

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NCBI Description of APOC1
The protein encoded by this gene is a member of the apolipoprotein C1 family. This gene is expressed primarily in the liver, and it is activated when monocytes differentiate into macrophages. A pseudogene of this gene is located 4 kb downstream in the same orientation, on the same chromosome. This gene is mapped to chromosome 19, where it resides within a apolipoprotein gene cluster. Alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined.

Community Annotation of APOC1 Add / Edit APOC1: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

APOC1 is highly significantly mutated in
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APOC1 is significantly mutated in
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APOC1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for APOC1