APOBEC3F Back

apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F

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NCBI Description of APOBEC3F
This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control. Alternatively spliced transcript variants encoding different isoforms have been identified.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

APOBEC3F is highly significantly mutated in
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APOBEC3F is significantly mutated in
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APOBEC3F is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for APOBEC3F