APOBEC3C Back

apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C

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NCBI Description of APOBEC3C
This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

APOBEC3C is highly significantly mutated in
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APOBEC3C is significantly mutated in
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APOBEC3C is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for APOBEC3C