apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1

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NCBI Description of APOBEC1

This gene encodes a member of the cytidine deaminase enzyme family. The encoded protein forms a multiple-protein editing holoenzyme with APOBEC1 complementation factor (ACF) and APOBEC1 stimulating protein (ASP). This holoenzyme is involved in the editing of C-to-U nucleotide bases in apolipoprotein B and neurofibromatosis-1 mRNAs.

Community Annotation of APOBEC1 Add / Edit APOBEC1: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


APOBEC1 is highly significantly mutated in
APOBEC1 is significantly mutated in
APOBEC1 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for APOBEC1