APOA2 Back

apolipoprotein A-II

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NCBI Description of APOA2
This gene encodes apolipoprotein (apo-) A-II, which is the second most abundant protein of the high density lipoprotein particles. The protein is found in plasma as a monomer, homodimer, or heterodimer with apolipoprotein D. Defects in this gene may result in apolipoprotein A-II deficiency or hypercholesterolemia.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

APOA2 is highly significantly mutated in
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APOA2 is significantly mutated in
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APOA2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for APOA2