APCDD1 Back

adenomatosis polyposis coli down-regulated 1

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NCBI Description of APCDD1

This locus encodes an inhibitor of the Wnt signaling pathway. Mutations at this locus have been associated with hereditary hypotrichosis simplex. Increased expression of this gene may also be associated with colorectal carcinogenesis.

Community Annotation of APCDD1 Add / Edit APCDD1: Annotations

No community annotations yet for APCDD1.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

APCDD1 is highly significantly mutated in
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APCDD1 is significantly mutated in
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APCDD1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for APCDD1