APBB3 Back

amyloid beta (A4) precursor protein-binding, family B, member 3

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NCBI Description of APBB3
The protein encoded by this gene is a member of the APBB protein family. It is found in the cytoplasm and binds to the intracellular domain of the Alzheimer's disease beta-amyloid precursor protein (APP) as well as to other APP-like proteins. It is thought that the protein encoded by this gene may modulate the internalization of APP. Multiple transcript variants encoding several different isoforms have been found for this gene.

Community Annotation of APBB3 Add / Edit APBB3: Annotations

No community annotations yet for APBB3.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

APBB3 is highly significantly mutated in
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APBB3 is significantly mutated in
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APBB3 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for APBB3