APBA3 Back

amyloid beta (A4) precursor protein-binding, family A, member 3 (X11-like 2)

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NCBI Description of APBA3

The protein encoded by this gene is a member of the X11 protein family. It is an adapter protein that interacts with the Alzheimer's disease amyloid precursor protein. This gene product is believed to be involved in signal transduction processes. This gene is a candidate gene for Alzheimer's disease.

Community Annotation of APBA3 Add / Edit APBA3: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

APBA3 is highly significantly mutated in
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APBA3 is significantly mutated in
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APBA3 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for APBA3