AP4M1 Back

adaptor-related protein complex 4, mu 1 subunit

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NCBI Description of AP4M1

This gene encodes a subunit of the heterotetrameric AP-4 complex. The encoded protein belongs to the adaptor complexes medium subunits family. This AP-4 complex is involved in the recognition and sorting of cargo proteins with tyrosine-based motifs from the trans-golgi network to the endosomal-lysosomal system.

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


AP4M1 is highly significantly mutated in
AP4M1 is significantly mutated in
AP4M1 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for AP4M1