AP3M2 Back

adaptor-related protein complex 3, mu 2 subunit

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NCBI Description of AP3M2

This gene encodes a subunit of the heterotetrameric adaptor-related protein comlex 3 (AP-3), which belongs to the adaptor complexes medium subunits family. The AP-3 complex plays a role in protein trafficking to lysosomes and specialized organelles. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Community Annotation of AP3M2 Add / Edit AP3M2: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

AP3M2 is highly significantly mutated in
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AP3M2 is significantly mutated in
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AP3M2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for AP3M2