AP2S1 Back

adaptor-related protein complex 2, sigma 1 subunit

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NCBI Description of AP2S1
One of two major clathrin-associated adaptor complexes, AP-2, is a heterotetramer which is associated with the plasma membrane. This complex is composed of two large chains, a medium chain, and a small chain. This gene encodes the small chain of this complex. Alternative splicing has been observed in this gene and results in two known transcripts.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

AP2S1 is highly significantly mutated in
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AP2S1 is significantly mutated in
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AP2S1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for AP2S1