AP2B1 Back

adaptor-related protein complex 2, beta 1 subunit

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NCBI Description of AP2B1
The protein encoded by this gene is one of two large chain components of the assembly protein complex 2, which serves to link clathrin to receptors in coated vesicles. The encoded protein is found on the cytoplasmic face of coated vesicles in the plasma membrane. Two transcript variants encoding different isoforms have been found for this gene.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

AP2B1 is highly significantly mutated in
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AP2B1 is significantly mutated in
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AP2B1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for AP2B1