AP1M1 Back

adaptor-related protein complex 1, mu 1 subunit

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NCBI Description of AP1M1
The protein encoded by this gene is the medium chain of the trans-Golgi network clathrin-associated protein complex AP-1. The other components of this complex are beta-prime-adaptin, gamma-adaptin, and the small chain AP1S1. This complex is located at the Golgi vesicle and links clathrin to receptors in coated vesicles. These vesicles are involved in endocytosis and Golgi processing. Alternatively spliced transcript variants encoding distinct protein isoforms have been found for this gene.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

AP1M1 is highly significantly mutated in
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AP1M1 is significantly mutated in
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AP1M1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for AP1M1