ANXA8 Back

annexin A8

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of ANXA8

This gene encodes a member of the annexin family of evolutionarily conserved Ca2+ and phospholipid binding proteins. The encoded protein may function as an an anticoagulant that indirectly inhibits the thromboplastin-specific complex. Overexpression of this gene has been associated with acute myelocytic leukemia. A highly similar duplicated copy of this gene is found in close proximity on the long arm of chromosome 10.

Community Annotation of ANXA8 Add / Edit ANXA8: Annotations

No community annotations yet for ANXA8.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


ANXA8 is highly significantly mutated in
ANXA8 is significantly mutated in
ANXA8 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for ANXA8