ANXA5 Back

annexin A5

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of ANXA5
The protein encoded by this gene belongs to the annexin family of calcium-dependent phospholipid binding proteins some of which have been implicated in membrane-related events along exocytotic and endocytotic pathways. Annexin 5 is a phospholipase A2 and protein kinase C inhibitory protein with calcium channel activity and a potential role in cellular signal transduction, inflammation, growth and differentiation. Annexin 5 has also been described as placental anticoagulant protein I, vascular anticoagulant-alpha, endonexin II, lipocortin V, placental protein 4 and anchorin CII. The gene spans 29 kb containing 13 exons, and encodes a single transcript of approximately 1.6 kb and a protein product with a molecular weight of about 35 kDa.

Community Annotation of ANXA5 Add / Edit ANXA5: Annotations

No community annotations yet for ANXA5.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

ANXA5 is highly significantly mutated in
(none)
ANXA5 is significantly mutated in
(none)
ANXA5 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for ANXA5