ANXA3 Back

annexin A3

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NCBI Description of ANXA3
This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions in the inhibition of phopholipase A2 and cleavage of inositol 1,2-cyclic phosphate to form inositol 1-phosphate. This protein may also play a role in anti-coagulation.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

ANXA3 is highly significantly mutated in
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ANXA3 is significantly mutated in
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ANXA3 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for ANXA3