ANXA2 Back

annexin A2

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NCBI Description of ANXA2
This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions as an autocrine factor which heightens osteoclast formation and bone resorption. This gene has three pseudogenes located on chromosomes 4, 9 and 10, respectively. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Community Annotation of ANXA2 Add / Edit ANXA2: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

ANXA2 is highly significantly mutated in
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ANXA2 is significantly mutated in
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ANXA2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for ANXA2