ANKK1 Back

ankyrin repeat and kinase domain containing 1

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NCBI Description of ANKK1

The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and protein kinase superfamily involved in signal transduction pathways. This gene is closely linked to DRD2 gene (GeneID:1813) on chr 11, and a well studied restriction fragment length polymorphism (RFLP) designated TaqIA, was originally associated with the DRD2 gene, however, later was determined to be located in exon 8 of ANKK1 gene (PMIDs: 18621654, 15146457), where it causes a nonconservative amino acid substitution. It is not clear if this gene plays any role in neuropsychiatric disorders previously associated with Taq1A RFLP.

Community Annotation of ANKK1 Add / Edit ANKK1: Annotations

No community annotations yet for ANKK1.
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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


ANKK1 is highly significantly mutated in
ANKK1 is significantly mutated in
ANKK1 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for ANKK1