ANKFY1 Back

ankyrin repeat and FYVE domain containing 1

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NCBI Description of ANKFY1
This gene encodes a cytoplasmic protein that contains a coiled-coil structure and a BTB/POZ domain at its N-terminus, ankyrin repeats in the middle portion, and a FYVE-finger motif at its C-terminus. This protein belongs to a subgroup of double zinc finger proteins which may be involved in vesicle or protein transport. Alternate splicing results in multiple transcript variants of this gene.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

ANKFY1 is highly significantly mutated in
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ANKFY1 is significantly mutated in
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ANKFY1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for ANKFY1