ANGPTL2 Back

angiopoietin-like 2

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NCBI Description of ANGPTL2
Angiopoietins are members of the vascular endothelial growth factor family and the only known growth factors largely specific for vascular endothelium. Angiopoietin-1, angiopoietin-2, and angiopoietin-4 participate in the formation of blood vessels. ANGPTL2 protein is a secreted glycoprotein with homology to the angiopoietins and may exert a function on endothelial cells through autocrine or paracrine action.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

ANGPTL2 is highly significantly mutated in
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ANGPTL2 is significantly mutated in
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ANGPTL2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for ANGPTL2