ANGPTL1 Back

angiopoietin-like 1

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NCBI Description of ANGPTL1
Angiopoietins are members of the vascular endothelial growth factor family and the only known growth factors largely specific for vascular endothelium. Angiopoietin-1, angiopoietin-2, and angiopoietin-4 participate in the formation of blood vessels. The protein encoded by this gene is another member of the angiopoietin family that is widely expressed in adult tissues with mRNA levels highest in highly vascularized tissues. This protein was found to be a secretory protein that does not act as an endothelial cell mitogen in vitro.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

ANGPTL1 is highly significantly mutated in
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ANGPTL1 is significantly mutated in
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ANGPTL1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for ANGPTL1