ANGPT4 Back

angiopoietin 4

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NCBI Description of ANGPT4
Angiopoietins are proteins with important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The mechanism by which they contribute to angiogenesis is thought to involve regulation of endothelial cell interactions with supporting perivascular cells. The protein encoded by this gene functions as an agonist and is an angiopoietin.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

ANGPT4 is highly significantly mutated in
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ANGPT4 is significantly mutated in
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ANGPT4 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for ANGPT4