anaphase promoting complex subunit 1

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NCBI Description of ANAPC1

This gene encodes a subunit of the anaphase-promoting complex. This complex is an E3 ubiquitin ligase that regulates progression through the metaphase to anaphase portion of the cell cycle by ubiquitinating proteins which targets them for degradation.

Community Annotation of ANAPC1 Add / Edit ANAPC1: Annotations

No community annotations yet for ANAPC1.
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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


ANAPC1 is highly significantly mutated in
ANAPC1 is significantly mutated in
ANAPC1 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for ANAPC1