angiomotin like 2

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NCBI Description of AMOTL2

Angiomotin is a protein that binds angiostatin, a circulating inhibitor of the formation of new blood vessels (angiogenesis). Angiomotin mediates angiostatin inhibition of endothelial cell migration and tube formation in vitro. The protein encoded by this gene is related to angiomotin and is a member of the motins protein family.

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


AMOTL2 is highly significantly mutated in
AMOTL2 is significantly mutated in
AMOTL2 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for AMOTL2