AMOTL1 Back

angiomotin like 1

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NCBI Description of AMOTL1
The protein encoded by this gene is a peripheral membrane protein that is a component of tight junctions or TJs. TJs form an apical junctional structure and act to control paracellular permeability and maintain cell polarity. This protein is related to angiomotin, an angiostatin binding protein that regulates endothelial cell migration and capillary formation.

Community Annotation of AMOTL1 Add / Edit AMOTL1: Annotations

No community annotations yet for AMOTL1.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

AMOTL1 is highly significantly mutated in
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AMOTL1 is significantly mutated in
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AMOTL1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for AMOTL1