alpha-1-microglobulin/bikunin precursor

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of AMBP

This gene encodes a complex glycoprotein secreted in plasma. The precursor is proteolytically processed into distinct functioning proteins: alpha-1-microglobulin, which belongs to the superfamily of lipocalin transport proteins and may play a role in the regulation of inflammatory processes, and bikunin, which is a urinary trypsin inhibitor belonging to the superfamily of Kunitz-type protease inhibitors and plays an important role in many physiological and pathological processes. This gene is located on chromosome 9 in a cluster of lipocalin genes.

Community Annotation of AMBP Add / Edit AMBP: Annotations

No community annotations yet for AMBP.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


AMBP is highly significantly mutated in
AMBP is significantly mutated in
AMBP is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for AMBP