ALX3 Back

aristaless-like homeobox 3

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NCBI Description of ALX3

This gene encodes a nuclear protein with a homeobox DNA-binding domain that functions as a transcriptional regulator involved in cell-type differentiation and development. Preferential methylation of this gene's promoter is associated with advanced-stage neuroblastoma tumors.

Community Annotation of ALX3 Add / Edit ALX3: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

ALX3 is highly significantly mutated in
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ALX3 is significantly mutated in
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ALX3 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for ALX3