ALPI Back

alkaline phosphatase, intestinal

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NCBI Description of ALPI

There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The intestinal alkaline phosphatase gene encodes a digestive brush-border enzyme. This enzyme is upregulated during small intestinal epithelial cell differentiation.

Community Annotation of ALPI Add / Edit ALPI: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

ALPI is highly significantly mutated in
(none)
ALPI is significantly mutated in
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ALPI is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for ALPI