ALKBH1 Back

alkB, alkylation repair homolog 1 (E. coli)

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NCBI Description of ALKBH1
This gene encodes a homolog to the E. coli alkB gene product. The E. coli alkB protein is part of the adaptive response mechanism of DNA alkylation damage repair. It is involved in damage reversal by oxidative demethylation of 1-methyladenine and 3-methylcytosine.

Community Annotation of ALKBH1 Add / Edit ALKBH1: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

ALKBH1 is highly significantly mutated in
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ALKBH1 is significantly mutated in
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ALKBH1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for ALKBH1