ALG5 Back

asparagine-linked glycosylation 5 homolog (S. cerevisiae, dolichyl-phosphate beta-glucosyltransferase)

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of ALG5
This gene encodes a member of the glycosyltransferase 2 family. The encoded protein participates in glucosylation of the oligomannose core in N-linked glycosylation of proteins. The addition of glucose residues to the oligomannose core is necessary to ensure substrate recognition, and therefore, effectual transfer of the oligomannose core to the nascent glycoproteins. Multiple transcript variants encoding different isoforms have been found for this gene.

Community Annotation of ALG5 Add / Edit ALG5: Annotations

No community annotations yet for ALG5.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

ALG5 is highly significantly mutated in
(none)
ALG5 is significantly mutated in
(none)
ALG5 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for ALG5