ALDOC Back

aldolase C, fructose-bisphosphate

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NCBI Description of ALDOC
This gene encodes a member of the class I fructose-biphosphate aldolase gene family. Expressed specifically in the hippocampus and Purkinje cells of the brain, the encoded protein is a glycolytic enzyme that catalyzes the reversible aldol cleavage of fructose-1,6-biphosphate and fructose 1-phosphate to dihydroxyacetone phosphate and either glyceraldehyde-3-phosphate or glyceraldehyde, respectively.

Community Annotation of ALDOC Add / Edit ALDOC: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

ALDOC is highly significantly mutated in
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ALDOC is significantly mutated in
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ALDOC is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for ALDOC