AKT1S1 Back

AKT1 substrate 1 (proline-rich)

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NCBI Description of AKT1S1
AKT1S1 is a proline-rich substrate of AKT (MIM 164730) that binds 14-3-3 protein (see YWHAH, MIM 113508) when phosphorylated (Kovacina et al., 2003 [PubMed 12524439]).[supplied by OMIM, Mar 2008].

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

AKT1S1 is highly significantly mutated in
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AKT1S1 is significantly mutated in
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AKT1S1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for AKT1S1