AKR1E2 Back

aldo-keto reductase family 1, member E2

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NCBI Description of AKR1E2

The protein encoded by this gene is a member of the aldo-keto reductase superfamily. Members in this family are characterized by their structure (evolutionarily highly conserved TIM barrel) and function (NAD(P)H-dependent oxido-reduction of carbonyl groups). Transcripts of this gene have been reported in specimens of human testis. Alternative splicing results in multiple transcript variants.

Community Annotation of AKR1E2 Add / Edit AKR1E2: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

AKR1E2 is highly significantly mutated in
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AKR1E2 is significantly mutated in
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AKR1E2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for AKR1E2