AKR1B10 Back

aldo-keto reductase family 1, member B10 (aldose reductase)

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NCBI Description of AKR1B10

This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member can efficiently reduce aliphatic and aromatic aldehydes, and it is less active on hexoses. It is highly expressed in adrenal gland, small intestine, and colon, and may play an important role in liver carcinogenesis.

Community Annotation of AKR1B10 Add / Edit AKR1B10: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

AKR1B10 is highly significantly mutated in
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AKR1B10 is significantly mutated in
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AKR1B10 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for AKR1B10