AKR1A1 Back

aldo-keto reductase family 1, member A1 (aldehyde reductase)

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NCBI Description of AKR1A1

This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member, also known as aldehyde reductase, is involved in the reduction of biogenic and xenobiotic aldehydes and is present in virtually every tissue. Multiple alternatively spliced transcript variants of this gene exist, all encoding the same protein.

Community Annotation of AKR1A1 Add / Edit AKR1A1: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

AKR1A1 is highly significantly mutated in
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AKR1A1 is significantly mutated in
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AKR1A1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for AKR1A1