AKAP7 Back

A kinase (PRKA) anchor protein 7

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NCBI Description of AKAP7
This gene encodes a member of the A-kinase anchoring protein (AKAP) family, a group of functionally related proteins that bind to a regulatory subunit (RII) of cAMP-dependent protein kinase A (PKA) and target the enzyme to specific subcellular compartments. AKAPs have a common RII-binding domain, but contain different targeting motifs responsible for directing PKA to distinct intracellular locations. Three alternatively spliced transcript variants encoding different isoforms have been described.

Community Annotation of AKAP7 Add / Edit AKAP7: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

AKAP7 is highly significantly mutated in
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AKAP7 is significantly mutated in
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AKAP7 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for AKAP7