AKAP10 Back

A kinase (PRKA) anchor protein 10

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of AKAP10
This gene encodes a member of the A-kinase anchor protein family. A-kinase anchor proteins bind to the regulatory subunits of protein kinase A (PKA) and confine the holoenzyme to discrete locations within the cell. The encoded protein is localized to mitochondria and interacts with both the type I and type II regulatory subunits of PKA. Polymorphisms in this gene may be associated with increased risk of arrhythmias and sudden cardiac death. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.

Community Annotation of AKAP10 Add / Edit AKAP10: Annotations

No community annotations yet for AKAP10.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

AKAP10 is highly significantly mutated in
(none)
AKAP10 is significantly mutated in
(none)
AKAP10 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for AKAP10