AKAP1 Back

A kinase (PRKA) anchor protein 1

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of AKAP1
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein binds to type I and type II regulatory subunits of PKA and anchors them to the mitochondrion. This protein is speculated to be involved in the cAMP-dependent signal transduction pathway and in directing RNA to a specific cellular compartment.

Community Annotation of AKAP1 Add / Edit AKAP1: Annotations

No community annotations yet for AKAP1.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

AKAP1 is highly significantly mutated in
(none)
AKAP1 is significantly mutated in
(none)
AKAP1 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for AKAP1