AIP Back

aryl hydrocarbon receptor interacting protein

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NCBI Description of AIP
The protein encoded by this gene is a receptor for aryl hydrocarbons and a ligand-activated transcription factor. The encoded protein is found in the cytoplasm as part of a multiprotein complex, but upon binding of ligand is transported to the nucleus. This protein can regulate the expression of many xenobiotic metabolizing enzymes. Also, the encoded protein can bind specifically to and inhibit the activity of hepatitis B virus.

Community Annotation of AIP Add / Edit AIP: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

AIP is highly significantly mutated in
(none)
AIP is significantly mutated in
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AIP is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for AIP