AIP Back

aryl hydrocarbon receptor interacting protein

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NCBI Description of AIP

The protein encoded by this gene is a receptor for aryl hydrocarbons and a ligand-activated transcription factor. The encoded protein is found in the cytoplasm as part of a multiprotein complex, but upon binding of ligand is transported to the nucleus. This protein can regulate the expression of many xenobiotic metabolizing enzymes. Also, the encoded protein can bind specifically to and inhibit the activity of hepatitis B virus.

Community Annotation of AIP Add / Edit AIP: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


AIP is highly significantly mutated in
AIP is significantly mutated in
AIP is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for AIP