AIFM2 Back

apoptosis-inducing factor, mitochondrion-associated, 2

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NCBI Description of AIFM2
This gene encodes a flavoprotein oxidoreductase that binds single stranded DNA and is thought to contribute to apoptosis in the presence of bacterial and viral DNA. The expression of this gene is also found to be induced by tumor suppressor protein p53 in colon cancer cells.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

AIFM2 is highly significantly mutated in
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AIFM2 is significantly mutated in
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AIFM2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for AIFM2