AIF1 Back

allograft inflammatory factor 1

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NCBI Description of AIF1

This gene is induced by cytokines and interferon. Its protein product is thought to be involved in negative regulation of growth of vascular smooth muscle cells, which contributes to the anti-inflammatory response to vessel wall trauma. Three transcript variants encoding different isoforms have been found for this gene.

Community Annotation of AIF1 Add / Edit AIF1: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


AIF1 is highly significantly mutated in
AIF1 is significantly mutated in
AIF1 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for AIF1