AHRR Back

aryl-hydrocarbon receptor repressor

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NCBI Description of AHRR
The protein encoded by this gene participates in the aryl hydrocarbon receptor (AhR) signaling cascade, which mediates dioxin toxicity, and is involved in regulation of cell growth and differentiation. It functions as a feedback modulator by repressing AhR-dependent gene expression. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Community Annotation of AHRR Add / Edit AHRR: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

AHRR is highly significantly mutated in
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AHRR is significantly mutated in
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AHRR is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for AHRR