AGRP Back

agouti related protein homolog (mouse)

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of AGRP
This gene encodes an antagonist of the melanocortin-3 and melanocortin-4 receptor. It appears to regulate hypothalamic control of feeding behavior via melanocortin receptor and/or intracellular calcium regulation, and thus plays a role in weight homeostasis. Mutations in this gene have been associated with late on-set obesity.

Community Annotation of AGRP Add / Edit AGRP: Annotations

No community annotations yet for AGRP.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

AGRP is highly significantly mutated in
(none)
AGRP is significantly mutated in
(none)
AGRP is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for AGRP