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acylglycerol kinase

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NCBI Description of AGK

The protein encoded by this gene is a mitochondrial membrane protein involved in lipid and glycerolipid metabolism. The encoded protein is a lipid kinase that catalyzes the formation of phosphatidic and lysophosphatidic acids. Defects in this gene have been associated with mitochondrial DNA depletion syndrome 10.

Community Annotation of AGK Add / Edit AGK: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

AGK is highly significantly mutated in
(none)
AGK is significantly mutated in
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AGK is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for AGK