AGFG1 Back

ArfGAP with FG repeats 1

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NCBI Description of AGFG1

The protein encoded by this gene is related to nucleoporins, a class of proteins that mediate nucleocytoplasmic transport. The encoded protein binds the activation domain of the human immunodeficiency virus Rev protein when Rev is assembled onto its RNA target, and is required for the nuclear export of Rev-directed RNAs. Multiple transcript variants encoding different isoforms have been found for this gene.

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


AGFG1 is highly significantly mutated in
AGFG1 is significantly mutated in
AGFG1 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for AGFG1