AGAP1 Back

ArfGAP with GTPase domain, ankyrin repeat and PH domain 1

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NCBI Description of AGAP1

This gene encodes a member of an ADP-ribosylation factor GTPase-activating protein family involved in membrane trafficking and cytoskeleton dynamics. This gene functions as a direct regulator of the adaptor-related protein complex 3 on endosomes. Multiple transcript variants encoding different isoforms have been found for this gene.

Community Annotation of AGAP1 Add / Edit AGAP1: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


AGAP1 is highly significantly mutated in
AGAP1 is significantly mutated in
AGAP1 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for AGAP1