AFG3L2 Back

AFG3 ATPase family gene 3-like 2 (yeast)

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NCBI Description of AFG3L2
This gene encodes a protein localized in mitochondria and closely related to paraplegin. The paraplegin gene is responsible for an autosomal recessive form of hereditary spastic paraplegia. This gene is a candidate gene for other hereditary spastic paraplegias or neurodegenerative disorders.

Community Annotation of AFG3L2 Add / Edit AFG3L2: Annotations

No community annotations yet for AFG3L2.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

AFG3L2 is highly significantly mutated in
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AFG3L2 is significantly mutated in
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AFG3L2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for AFG3L2